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|CHICAGO Adriano Jersey , Dec. 11 (Xinhua) -- Diabetes is known to increase a person's risk of kidney disease. Now, the converse is also true: Kidney dysfunction increases the risk of diabetes, according to a study of Washington University School of Medicine in St. Louis.
Researchers further deduced that a likely culprit of the two-way relationship between kidney disease and diabetes is urea, the nitrogen-containing waste product in blood that comes from the breakdown of protein in foods. Kidneys normally remove urea from the blood, but it can build up when kidney function slows down.
Researchers examined medical records in national databases and evaluated the records of 1.3 million adults without diabetes over a five-year period, beginning in 2003.
A common blood test that measures the amount of urea nitrogen found in the blood showed that 117,000 of those without diabetes Adrian Ortola Jersey , or 9 percent, had elevated urea levels, signaling poor kidney function.
Overall, those with high urea levels had a 23 percent higher risk of diabetes. In each year studied, the researchers documented new cases of diabetes in 2,989 of every 100,000 people with low urea levels and 3 Customized Barcelona Jersey ,677 new cases of diabetes among those with high urea levels.
"The risk difference between high and low levels is 688 cases of diabetes per 100,000 people each year," said the study's senior author Ziyad Al-Aly, an assistant professor of medicine at Washington University in St. Louis. "This means that for every 100,000 people, there would be 688 more cases of diabetes each year in those with higher urea levels."
In a mouse study published in the August 2016 Journal of Clinical Investigation, researchers induced kidney failure in mice. Subsequently Cheap Barcelona Jersey , many of the animals experienced elevated urea levels, resulting in insulin resistance and impaired insulin secretion.
Al-Aly tested this in human. "Our results were almost an exact replica of the mouse study. The results showed a clear relationship between urea levels and risk of diabetes," he said.
The findings are significant because urea levels can be lowered through medication, diet and other means, thereby allowing for improved treatment and possible prevention of diabetes.
The study was published in Kidney International on Monday.
TAIYUAN, Nov. 6 (Xinhua) -- Shanxi, China's major coal-producing province Xavi Hernandez Barcelona Jersey , is trying to develop emerging industries such as mobile phone manufacturing to reduce its reliance on coal and transform its economy.
Mobile phones have become the province's top export product, with an export volume of 38 billion yuan (around 5.7 billion U.S. dollars) in 2016, accounting for 58 percent of total exports, according to the provincial department of commerce.
In the first three quarters of 2017, Shanxi exported more than 16 million mobile phones and the export volume exceeded 27 billion yuan, the department said.
"The province has developed an industrial chain involving mobile phone manufacturing, sales Thomas Vermaelen Barcelona Jersey , recycling and repairs," said Li Guorong, head of foreign trade bureau with the department.
With a quarter of China's proven coal reserves, Shanxi has shut down lots of coal mines and reduced production capacity amid the country's efforts to cut excess capacity and improve efficiency in coal industry.
The local government began focusing on innovative and export-oriented companies developing strategic emerging industries, such as information technology, biological medicine and advanced equipment manufacturing.
"When the coal industry has lower impact on Shanxi's economy, we can say our economic transformation and upgrading efforts have been successful Sergio Busquets Barcelona Jersey ," Li said.
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